The ELIPSE Study - a randomised controlled trial comparing the clinical and cost-effectiveness of lymph node removal in patients undergoing curative surgery for localised high-risk prostate cancer.

Plain English Summary:

Research Question Does Pelvic Lymph Node Dissection (PLND) provide better cancer control compared to no PLND in patients undergoing surgery (radical
prostatectomy, RP) for localised high-risk prostate cancer (PCa_? Aims and Objectives To determine the clinical and cost effectiveness of RP + PLND versus
RP alone in patients undergoing surgery for localised high-risk Pca. 1. Primary objectives: Compare RP+ PLND and RP alone in terms of cancer r...

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Abstract:

BACKGROUND Around 50,000 people are diagnosed with prostate cancer annually in the UK, and over 10,000 people die from it. Prostate cancer that has not
spread elsewhere in the body but is at risk of doing so is referred to as high-risk prostate cancer. In the UK, 4000 patients a year get surgery for high-risk
prostate cancer. The operation involves removal of the entire prostate gland and, in some cases, also the nearby lymph nodes from the pelvis. ...

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Chief Investigator(s):

Mr Krishna Narahari